WLS utility function.
scMultiMap_WLS_by_gene.RdThis function performs WLS for one gene and all peaks in its candidate pairs.
Usage
scMultiMap_WLS_by_gene(
x_gene,
X_peak,
m_gene,
M_peak,
w_gene,
W_peak,
var_gene,
Var_peak,
gene_seq_depth,
peak_seq_depth
)Source
Cell-type-specific mapping of enhancer and target genes from single-cell multimodal data. Chang Su, Dongsoo Lee, Peng Jin, Jingfei Zhang;
Arguments
- x_gene
A length n vector of gene counts. n denotes the number of cells.
- X_peak
A n by p peak count matrix. p denotes the number of peaks.
- m_gene
A length n vector of gene counts' mean across cells.
- M_peak
A n by p matrix of peak counts' mean across cells for all peaks.
- w_gene
A length n vector used to calculate regression weights.
- W_peak
A n by p matrix used to calculate regression weights.
- var_gene
A length n vector of gene counts' variance across cells.
- Var_peak
A n by p matrix of peak counts' variance across cells for all peaks.
- gene_seq_depth
A length n vector of sequencing depths from the RNA modality.
- peak_seq_depth
A length n vector of sequencing depths from the ATAC/peak modality.